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Can You Safely Combine Trazodone With Phenobarbital?

Phenobarbital: Uses, Side Effects, Warnings & More - Goodrx

Can You Safely Combine Trazodone With Phenobarbital?

Legal High But Is It Safer?

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Does Trazodone Interact With Seizure Medication?

Certainly! Here is the revised passage with additional information for better understanding:

“Can trazodone interact with seizure medication? Yes, there are potential interactions between trazodone, an antidepressant, and certain antiepileptic drugs. These interactions may be attributed to pharmacodynamic effects, which involve how the drugs affect the body.

Both acute and long-term use of trazodone have been found to reduce the concentration of phenytoin in the brain. Additionally, chronic use of trazodone has been observed to lower the levels of carbamazepine and phenobarbital in the brain. This means that if a person is taking trazodone for depression while also using phenytoin, carbamazepine, or phenobarbital for seizure control, it’s important for their healthcare provider to monitor their medication levels and adjust doses if necessary to ensure optimal therapeutic effects.”

What Drugs Should Not Be Taken With Trazodone?

Trazodone is a medication that should not be taken in combination with certain other drugs, as it can lead to potentially harmful interactions. To ensure your safety and the effectiveness of your treatment, it is crucial to avoid using trazodone alongside specific medications. These medications include buspirone (brand name: Buspar®), fentanyl (brands: Abstral®, Duragesic®), lithium (brands: Eskalith®, Lithobid®), tryptophan, and St. John’s wort. Additionally, caution should be exercised when taking trazodone with certain pain or migraine medications, such as sumatriptan, tramadol, Frova®, Maxalt®, Relpax®, and Zomig®. Combining trazodone with any of these substances may result in adverse effects, so it’s important to consult with your healthcare provider to determine the safest and most suitable treatment plan for your specific needs.

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Categories: Details 15 Can You Take Trazodone With Phenobarbital

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Legal high but is it safer?
Legal high but is it safer?

Using PHENobarbital together with traZODone may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination.Some interactions between trazodone and antiepileptic drugs may have a pharmacodynamic background. Both, acute and chronic treatment with the antidepressant diminished the brain concentration of phenytoin. Chronic trazodone lowered the brain levels of carbamazepine and phenobarbital.Do not use trazodone with buspirone (Buspar®), fentanyl (Abstral®, Duragesic®), lithium (Eskalith®, Lithobid®), tryptophan, St. John’s wort, or some pain or migraine medicines (eg, sumatriptan, tramadol, Frova®, Maxalt®, Relpax®, Zomig®).

This medication may also interact with the following:
  • Alcohol or medications that contain alcohol.
  • Antihistamines.
  • Medications for depression, anxiety, or mental health conditions.
  • Medications for pain including pentazocine, buprenorphine, butorphanol, nalbuphine, tramadol, and propoxyphene.
  • Medications for sleep.

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